Set in 2022, this case describes the considerations involved in organizing the physical relocation of the Rowland Institute at Harvard (RIH), a research institute established in 1980 by Edwin H. Land, the founder of the Polaroid Corporation, for the advancement of science. After 43 years at 100 Edwin H. Land Boulevard, the RIH needs a new home. As she evaluates available options, Leigh Needleman, the executive director of the Institute, not only has a long legacy to consider but must also decide where to relocate, whether to buy or rent the new space, and how to assign new laboratory and office spaces to staff to best foster breakthrough science and innovation.