The nature of work is changing-and it is changing rapidly. Few days go by without industry giants such as Amazon and AT&T announcing plans to invest billions of dollars towards retraining nearly half of their respective workforces for jobs of the future. What changes lurking around the corner are Amazon and AT&T seeing? What tools do managers have to confront the accelerating change? How should talent management and workplace design evolve for the new landscape? This note summarizes the key drivers of change and offers a framework for managers to apply to their businesses.