Michael Ku joined Pfizer in 2011, after the company had undergone three large-scale mergers and acquisitions. His mission was to drive the digital transformation of the company's clinical supply chain, but he knew he had to start with the culture. Over the next eight years, Ku and his leadership team put in place the culture, talent, structure, and processes necessary to prime the clinical supply chain for digital transformation. By 2019, the clinical supply chain had made significant progress toward becoming the agile, innovative organization necessary to support Pfizer's new ambition to focus exclusively on developing innovative medicines and vaccines. Ku knew there was more to be done before they could maximize their digital and innovation efforts. He had asked his leadership team to come up with a proposal to improve decision-making in the organization.