This case is a follow up to HBS Case No.CCJB-HBS-721373, Takeda Pharmaceutical Company Limited (A). Following the events of the previous case, Takeda reached an agreement to acquire Ireland-based Shire Plc. The case follows some of the achievements and challenges Takeda and its employees face following the acquisition. It outlines the company's situation in 2019 and raises discussion about its future prospects.